Senior Scientist, Biology
Xaira TherapeuticsSouth San Francisco, California, United States · Posted 1 day agoDescription
About Xaira Therapeutics
Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.
About the Role
Xaira Therapeutics is seeking a lab-based Senior Scientist in Inflammation and Immunology to join our Biology & Pharmacology department. This role is ideal for someone who thrives in a hands-on research environment, has experience working with primary human and mouse immune cells, including ex vivo tissue systems, and is excited to help shape therapeutic program strategy.
In this role, you will investigate disease biology and drug mechanisms, generate actionable data, and intellectually contribute to advancing therapeutic programs through cross-functional collaborations.
What You’ll Do
- Drive preclinical programs by designing, executing and analyzing in vitro and in vivo studies that explore disease biology, target validation, and lead candidate development.
- Identify knowledge gaps, ask critical mechanistic questions to guide program direction, and evaluate novel targets and therapeutic strategies.
- Dissociate human and mouse tissues into single-cell suspensions and/or establish tissue cultures for downstream functional or phenotyping assays including:
- immune profiling, using high-parameter flow cytometry (15+ colors), and molecular tools (ELISA, MSD, Luminex, qPCR, RNAseq analyses).
- functional assays (antigen presentation, immune cell activation, differentiation, proliferation, suppression, migration)
- Translate experimental data into actionable insights and clearly communicate findings and recommendations to cross-functional teams.
What We’re Looking For
- PhD in Immunology or a related field with 3+ years of relevant experience.
- Track record of impact through first author publications, posters and presentations at meetings
- Hands-on experience with primary human and mouse immune cells.
- Strong expertise in flow cytometry, including high-parameter panel design, execution, and data analysis.
- Proven ability to independently plan, execute, troubleshoot, and interpret experiments.
- Excited about employing AI tools in every aspect of everyday work.
- Highly organized and precise in record keeping, with the ability to manage multiple workstreams in a fast-paced environment.
- Clear communicator who can distill complex data into actionable insights.
Compensation
We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. We offer a competitive package that includes base salary, bonus, and equity. The base pay range for this position is expected to be $140,000 - $170,000 annually; however, the base pay offered may vary depending on the market, job-related knowledge, skills and capabilities, and experience.
Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.
TO ALL RECRUITMENT AGENCIES: Xaira Therapeutics does not accept agency resumes. Please do not forward resumes to our jobs alias or employees. Xaira Therapeutics is not responsible for any fees related to unsolicited resumes.
Similar jobs
Est. 153,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 217,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 238,500 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 153,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 166,500 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 180,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 261,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 205,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 139,500 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 193,500 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 217,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 139,500 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 287,500 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 145,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 165,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 144,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 120,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 107,200 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 147,500 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 120,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 220,000 USD
Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic condition…
Est. 140,000 USD
Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease. The future is coming. A future enabled and enric…
Est. 80,000 GBP
Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease. The future is coming. A future enabled and enric…
Est. 201,000 USD
Your Impact at LILA We are seeking a Senior Principal Scientist, Small Molecule Therapeutics to lead the protein science and structural biology strategy supporting small molecule therapeutics across Lila’s discovery plat…
Est. 155,000 USD
What if you could join a rapidly growing company and play a critical role in bringing new medicines to patients through looking at and treating disease in a revolutionary way. What this position is all about: Are you a h…
Est. 80,000 USD
Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery,…
Est. 125,000 USD
Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA…
Est. 140,000 USD
Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease. The future is coming. A future enabled and enric…
Est. 204,750 USD
About Formation Bio Formation Bio is a tech and AI driven pharma company differentiated by radically more efficient drug development. Advancements in AI and drug discovery are creating more candidate drugs than the indus…
Est. 220,000 USD
Your Impact at LILA Lila Sciences is hiring a Director of Product, Life Sciences (Chemistry): a strategic, cross-functional product leader who shapes the vision, roadmap, and execution for platforms that accelerate the d…